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Graduate Student Supervision

1 Cassandra Bishop Robinson

2 Deidra Atkins

3 Karen McClendon

4 Carma D. Hodge

5 Shorye Payne

6 Stephanie Talton

Mentor to College/High School Students

1 Tamra Gentry, 1995 Summer College Student

2 Ike Onwere, 1995 Summer NIH attachee

3 Carter Smith, 1996 Summer College Student

4 Jeff Smith, 1995 High School Student

5 Shan Duseja, 1994 High School Student

Mentor to Post-Doctoral Fellows and Residents

1 Dr. Amitabha Chakrabarti (1993-1999)

2 Dr. Saba Abaci (1998)

3 Dr. E. T. Gwebu: Sabbatical on cannabinoid receptor gene expression

Mentoring at William Paterson University

1 Chiara Brandoni, Independent Study on interaction of rimonabant on withdrawal from cocaine chronic cocaine treatment 2002.

2 Danille Colas. Behavioral effects of capsaicin 2003.

3 David Niglo: Independent Reading 2003.

4 Alex Perchuk: Independent Study. Prenatal exposure to capsaicin, 2004.

5 List of current students from 2003 include: Zoila Mora, Derrick Rodriguez, Lester Myers, Caroline Schmidt, Jocelyn Dexter

Committees and other special assignments

1 Institutional Animal and Use Committee (IACUC) member, 1994-1996

2 MBRS grant advisory committee, 1994-1996

3 Neuroscience day symposium (1995), member and speaker

4 Cardiovascular Training grant: Co-Pi and advisory committee member, 1994-1996

5 Faculty Welfare Committee (1995 – 1996)

6 Vanderbilt committee on Behavioral Genetics (1997)

7 Role model Scientist by Science Museum of Nashville, 1994

Committees and other special assignments at William Paterson University

1. Department of Biology Seminar Co-ordinator 2000-Present.

2. Student and ad hoc biotechnology committee 2000-2003.

3. Pre-professional, Technician Review, Undergraduate curriculum, Technology and Senate, Athletic activities council committees. 2003-Present.

Invited Speaker and Presentations

· Behavioral and biochemical consequences of MPTP infusion into substantia nigra and caudate putamen of the rat brain, Florida A & M University, Tallahassee, 1990.

· The application of some behavioral and biochemical techniques to assess drug action in the brain; LSUMC, New Orleans (1990) and at Sheveport (1991), LA and at Southern University, Baton Rouge, 1990; and at Ohio Northern University, Ada, (1992)

· Potential application of 5-HT agents in schizophrenia; Stanford University Mental health Clinical Research Center. 1991

· A comparison of behavioral and [³H]BDZ binding in three rat strains. Morehouse School of Medicine in Atlanta, GA, 1991

· Cellular and molecular biological approaches to further understand dopamine function in the CNS. University of Pennsylvania, Smell and Taste Center, Philadelphia, PA, 1991

· Cultural and brain research methods in Africa. International speakers bureau (Bechtel International Center, Stanford University, for Gun High School Int. Festival, 1992

· Animal behavioral models for the study of anxiety. Synthex Inc. Palo Alto, 1992

· Predicting drugs with abuse potential using the two compartment black and white box, Synaptic Pharmaceutical Corporation, Paramus, NJ, 1992

· Animal behavioral models to study drug action in the brain. Visiting lecturer to the Department of Anesthesiology Grand Rounds, University of California, Davis, CA, 1992

· Are there subtypes of cannabinoid receptors in the brain. Kirksville College of Osteopatic Medicine, 1993.

· Molecular correlates of behavioral changes in assessing drug action in the central nervous system, Vanderbilt University, 1993.

· Neural Networks to predict neurobehavioral effects in the rodent model. Presentation to Tennessee State University and Meharry Medical College Collaborating group, 1994.

· Neurobiological basis of emotionality. Presented to organic chemistry, biochemistry and psychology students and faculty at Oakwood College. April 26 and 27, 1994.

· Are there subtypes of marijuana receptors in the brain. Presented during the membrane biology research symposium sponsored by Meharry Center of Excellence in cell and molecular biology. May 9, 1994.

· Neurobiological bases of the action of psychostimulants in the hippocampus. Presented at the satellite meeting of the International society of Neurochem in Niigata, Japan. 1995.

· Aggression and hyperactivity following lesions of the raphe nuclei: Behavioral and neurochemical correlates. Presented at the 1995 Neuroscience symposium on Violence and aggression-the neurochemical basis at Meharry Medical College. July 20-21, 1995.

· Molecular bases for neurobehavioral changes. Temple University School of Pharmacy, December 6, 1995.

· Animal models to study brain function. Elizabeth-City State University, NC. 2/8/96.

· Meharry representative on the 23rd annual symposium: Increasing Health career opportunities. A 16 Institutions Health Sciences consortium. Greensboro, NC, 1996.

· Cannabinoid induced neurobehavioral alteration. Morehouse School of Medicine, 1996.

· Recent advances in cannabinoid research. Presented to the Vanderbilt Addiction Medicine Rounds 1997.

· The use of genetically altered mice for neurobehavioral analysis. Presented at the Lawrence Livermore National laboratory, Livermore, CA, 1998.

· Cannabinoid receptor genetics and behavior. Presented at the International Cannabinoid Research Society in Montpellier, France, 1998.

· Cannabinoid receptor genetics and behavior. Presented at the University of Mississippi, Oxford, MS, 1999.

· Molecular genetic approaches in to cannabinoid research. Presented to the Molecular Neurobiology branch at NIDA intramural program in Baltimore, March, 2000.

· Progress in Cannabis Research. Presented at Columbia University’s division on substance abuse monthly seminar on 9/26/02.

· Ibogaine Research. Presented at Harlem builds NYC support for ibogaine and iboga access at the Dempsey center in NY on 11/16/2002.

· Cannabinoid Research Up date. Presented at the Psychiatry Department treatment research center at UPENN on 01/27/2003.

· Cannabinoid Genomics. Presented at University of Buenos Aires on 03/18/2003.

Dissertation

1 Onaivi, E. S: Behavioral and biochemical consequences of bilateral and unilateral infusion of 1-methyl-4-phenyl-1, 2,3,6-tetrahydropridine (MPTP) into the caudate putamen and substantia nigra of the rat brain. M.Sc. dissertation, University of Bradford, Eng land, 1985.

2 Onaivi, E. S : Development of behavioral models for the assessment of drug action on cerebral 5-hydroxytryptamine function. Doctoral dissertation. University of Bradford England, 1987.

Publications

1. Bradbury A.J., Costall, B. Naylor, RJ. and E.S. Onaivi: 5-Hydroxytryptamine involvement in the locomotor activity suppressant effects of amphetamine in the mouse. Psychopharmacology 93: 457-465, 1987.

2. Costall B., Kelly M.E., Naylor R.J. and Onaivi E.S.: The actions of nicotine and cocaine in a mouse model of anxiety. Pharmacology, biochemistry and Behavior. 33(1): 197-203, 1988.

3. Onaivi E.S. and B.R. Martin: Behavioral effects in the mouse during and following withdrawal from repeated ethanol and nicotine administration. Nida Research Monograph 90. Problems of drug dependence 355, 1988.

4. Costall B., Kelly M.E., Naylor R.J. and E.S. Onaivi: Actions of buspirone in a putative model of anxiety in the mouse. J. Pharm. Pharmacol. 40: 494-500, 1988.

6. Onaivi E.S. and B.R. Martin: A neuropharmacological and physiological validation of a computer-controlled two-compartment black and white box for the assessment of anxiety. Prog. Neuro-Psychopharmacol & Biol. Psychiatry, 13: 963-976, 1989.

7. Costall B., Kelly M.E., Naylor R.J. and E.S., and M.B. Tyers: Neuroanatomical sites of action of 5-HT₃ receptor agonist and antagonists for alteration of aversive behavior in the mouse. Br. J. Pharmacol. 96: 325-332, 1989.

8. Onaivi E.S., Todd S. and B.R. Martin: Behavioral effects in the mouse during and following withdrawal from ethanol ingestion and/or nicotine administration. Drug and Alcohol Dependence. 24:205-211, 1989.

9. Martin B.R., Onaivi E.S. and T.J. Martin. What is the nature of mecamylamine's antagonism of the central effects of nicotine. Biochemical Pharmacology, 38(20):3391-3397, 1989.

10. Costall B., Kelly M.E., Onaivi E.S. and Naylor R.J.: The effect of ketotifen in rodent models of anxiety and on the behavioral consequences of withdrawing from treatment with drugs of abuse. Naunyn-Schmiedebergs Archives of Pharmacology, 1990, June, 341(6): 547-551.

11. Singh V.B., Onaivi E.S., Tam-Hao Phan, and Margaret C. Boadle-Biber: The increase in rat cortical and midbrain tryptophan hydroxylase activity in response to acute or repeated sound stress are blocked by bilateral lesions to the central nucleus of the amygdala. Brain Research 530: 49-53, 1990.

12. Costall B., Jones B.J., Kelly M.E., Onaivi E.S., Naylor R.J. and M.B. Tyers: Odansetron inhibits a behavioral consequence of withdrawing from drugs of abuse. Pharmacol. Biochemist and Behav. 1990 June, 36(2): 339-344.

13. Onaivi E.S., Green M.R. and B.R. Martin: Pharmacological characterization of cannabinoids in the Elevated-Plus Maze. J. of Pharmacol. & Exp. Ther., 253(3): 1002-1009., 1990.

14. Costall B., Jones B.J., Kelly M.E., Naylor R.J., Oakley N.R., Onaivi E.S. and M.B. Tyers. The effects of Ondansetron (GR38032F) in rats and mice treated subchronically with diazepam. Pharmacol. Biochem. Behav., 34: 769-778. 1990.

15. Barnes J.M., Costall B., Coughlan J., Domeney A.M., Gerrard P.A., Kelly M.E., Naylor R.J., Onaivi E.S., Tomkins D.M. and M.B. Tyers: The effects of Ondansetron, a 5-HT₃receptor antagonist, on cognition in rodents and primates. Pharmacology Biochemistry and Behavior, 35:955-962, 1990.

16. Costall B., Jones B.J., Kelly M.E., Onaivi E.S., Naylor R.J., and M.B. Tyers: Sites of action of Odansetron to inhibit withdrawal from drugs of abuse. Pharmacology, Biochemistry and Behavior, 1990 May, 36(1): 97-104.

17. Barnes NM, Costall B., Kelly M.E., Onaivi E.S. and Naylor R.J.: Ketotifen and its analogues reduce aversive responding in the rodent. Pharmacology, biochemistry and Behavior 37(4): 785-793, 1990.

18. Prasad C, Hilton C.W., Szec C, Onaivi E.S. and P. Vo: Could dietary proteins serve as Cyclo His Pro precursors. Neuropetide 19: 17-21, 1991.

19. Onaivi E.S., Talton S, and C. Prasad. The level of protein in diet modulates the behavioral effects of amphetamine. Book Chapter Endocrine and Nutritional Control of Basic Biological Functions, H. Lehnert R. Murison, H. Weiner, D. Hellhammer and J. Beyer (Eds), 1991.

20. Hamdi A., Onaivi E.S. Farooqui S, and C. Prasad. Levels of Protein in diet modulates dopamine receptor. Life Science 50: 1529-1534, 1992.

21. Salonen M, Onaivi E.S., and Maze M. Dexmedetomidine synergism with midazolam in the elevated plus-maze in rats. Psychopharmacology 108: 229-234, 1992.

22. Onaivi E.S., Brock J.W., and C. Prasad. Dietary protein levels alter rat behavior. Nutrition Research. 12: 1025-1039, 1992.

23. Onaivi E.S., Maguire P. Davies F, and Loew G. Comparison of the behavioral and central BDZ binding profile in three rat strains. Pharmacol. Biochem. Behavior 43(3): 825-831 (1992).

24. Akinshola, B. E., Chakrabarti, A. and Onaivi, E. S. In-vitro and in-vivo action of cannabinoids. Neurochemical Research 24(10): 1235-1242, 1999.

25. Akinshola, B. E., Taylor, R. E., Ogunsitan, A. B. and Onaivi, E. S. Anandamide inhibition of recombinant AMPA receptor subunits in xenopus oocytes is increased by forsko lin and 8-bromo-cyclic AMP. Naunyn-Schmiedeberg’s Arch Pharmacol. 360: 242-248, 1999.

26. Hubbard, J. R., Franco, S. E. and Onaivi, E. S. Marijuana: Medical Implications. Am

Fam Physcian 60: 2583-93, 1999.

27. Onaivi, E. S., Ali, S. F and Chakrabarti, A. In-vivo ibogaine blockade and in-vitro PKC action of cocaine. Annals New York Acad. Sci. 844: 227-244, 1998.

28. Onaivi, Emmanuel S., Gautam Chaudhuri, Asli S. Abaci, Monica Parker, Donald H. Manier, Peter R. Martin and John R. Hubbard: Expression of cannabinoid receptors and their gene transcripts in human blood cells. Prog. Neuro-Psychopharmacol. & Biol. Psychiat. 23: 1063-1077, 1999.

29. Onaivi, E. S., Reggio, P. H. and Chakrabarti, A. Genes encoding marijuana receptors. NIDA Res. Monog., 178: 238, 1998.

30. Brock, J. W., Farooqui, S. M., Onaivi, E. S., Hamdi, A. and Prasad, C. Dietary protein and central monoamine concentrations in the rat. Nutritional Neuroscience 1: 69-76, 1998.

31. Chakrabarti, A., Ekuta, J. E. and Onaivi, E. S. Neurobehavioral effects of anandamide and cannabinoid receptor gene expression in mice. Brain Res. Bulletin 45: 67-74, 1998.

32. Stubbs, L., Chittenden, L., Chakrabarti, A and Onaivi E. S. The mouse cannabinoid receptor gene is located in proximal chromosome 4. Mammalian Genome, 7: 165-166, 1996.

33. Onaivi, E. S., Chakrabarti, A and Chaudhuri, G. Cannabinoid receptor genes. Progress in Neurobiology, 48: 275-305, 1996.

34. Onaivi, E. S., Bishop-Robinson, C.,Chakrabarti, A., Motley, E. D and Chirwa, S. S Neurobiological actions of cocaine in the hippocampus. Ann. NY Acad. Sci., 801: 76-94, 1996.

35. Onaivi E.S. Changes in dopamine, DA-D₂ receptor mRNA expression following apomorphine induced hyothermia and Stereotypy. NeuroReport 4, 703-705. 1993.

36. Davies, M. F., Onaivi, E. S., Chen, S. -W., Maguire, P., Tsai, N. F and Loew, G. Evidence for central BDZ receptor heterogeneity from behavior tests. Pharmacol. Biochem. Behav. 49, 47-56, 1994.

37. Prasad C, Ikegami, H., Shimizu, I. and Onaivi, ES. Chronic nicotine intake decelerates aging of nigrostriatal dopaminergic neurons. Life Sciences 54: 1169-1184, 1994.

38. Farooqui, S., Brock, J. W., Onaivi, E. S., Hamdi, A and Chandan Prasad. Differential modulation of dopaminergic systems in the rat brain by dietary protein. Neurochemical Research, 19: 167-176. 1994.

39. Onaivi, E. S., Payne, S., Brock, J. W., Hamdi, A., Farooqui, S. and Prasad. Chronic nicotine reverses age-associated increase in tail-flick latency and anxiety in rats. Life Sciences, 54: 193-202, 1994.

40. Onaivi, E. S., Bishop-Robinson, C., Darmani, N. A. and Sanders-Bush, E. Behavioral effects of (±)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane, (DOI) in the elevated plus-maze. Life Sciences, 57: 2455-2466, 1995.

41. Chakrabarti, A., Onaivi, E. S. and Chadhuri, G. Cloning and sequencing of a cDNA encoding the mouse brain-type cannabinoid receptor protein. DNA Sequence 5(6): 385-388, 1995.

42. Onaivi, E. S., Chakrabarti, A., Gwebu, E. T. and Chaudhuri, G. Neurobehavioral effects of delta-9-THC and cannabinoid receptor gene expression in mice. Behavioral Brain Research 72(1-2): 115-125, 1995 .

43. Onaivi, E. S., Bishop-Robinson, C.,Chakrabarti, A., Motley, E. D and Chirwa, S. S Neurobiological actions of cocaine in the hippocampus. Ann. NY Acad. Sci., 801: 76-94, 1996.

44. Onaivi, E. S., Chakrabarti, A and Chaudhuri, G. Cannabinoid receptor genes. Progress in Neurobiology, 48: 275-305, 1996.

45. Stubbs, L., Chittenden, L., Chakrabarti, A and Onaivi E. S. The mouse cannabinoid receptor gene is located in proximal chromosome 4. Mammalian Genome, 7: 165-166, 1996.

46. Chakrabarti, A., Ekuta, J. E. and Onaivi, E. S. Neurobehavioral effects of anandamide and cannabinoid receptor gene expression in mice. Brain Res. Bulletin 45: 67-74, 1998.

47. Brock, J. W., Farooqui, S. M., Onaivi, E. S., Hamdi, A. and Prasad, C. Dietary protein and central monoamine concentrations in the rat. Nutritional Neuroscience 1: 69-76, 1998.

48. Onaivi, E. S., Ali, S. F and Chakrabarti, A. In-vivo ibogaine blockade and in-vitro PKC action of cocaine. Annals New York Acad. Sci. 844: 227-244, 1998.

49. Onaivi, E. S., Reggio, P. H. and Chakrabarti, A. Genes encoding marijuana receptors. NIDA Res. Monog., 178: 238, 1998.

50. Akinshola, B. E., Chakrabarti, A. and Onaivi, E. S. In-vitro and in-vivo action of cannabinoids. Neurochemical Research 24(10): 1235-1242, 1999.

51. Akinshola, B. E., Taylor, R. E., Ogunsitan, A. B. and Onaivi, E. S. Anandamide inhibition of recombinant AMPA receptor subunits in xenopus oocytes is increased by forskolin and 8-bromo-cyclic AMP. Naunyn-Schmiedeberg’s Arch Pharmacol. 360: 242-248, 1999.

52. Hubbard, J. R., Franco, S. E. and Onaivi, E. S. Marijuana: Medical Implications. Am Fam Physcian 60: 2583-93, 1999.

53. Onaivi, Emmanuel S., Gautam Chaudhuri, Asli S. Abaci, Monica Parker, Donald H. Manier, Peter R. Martin and John R. Hubbard: Expression of cannabinoid receptors and their gene transcripts in human blood cells. Prog. Neuro-Psychopharmacol. & Biol. Psychiat. 23: 1063-1077, 1999.

54. Arinami, T., Ishiguro H. and Onaivi, E. S. Polymorphisms in genes involved in neurotransmission in relation to smoking. Eur J Pharmacol. 410: 215-226, 2000.

55. Zhang, Z. J., Schmidt, D. E., de Paulis, T., Trivedi, B. E., Onaivi, E. S, Ebert, M. H and Hewlett, W. A. Anxiolytic-like effects of DAIZAC, a selective high-affinity 5-HT₃ receptor antagonist, in the mouse elevated plus-maze. Pharmacol. Biochem Behav. 69: 571-578, 2001.

56. Onaivi, E. S., Akinshola, B. E and Ali, S. F. Changes in gene expression and signal transduction following ibogaine treatment. Alkaloids Chem Biol. 56: 135-153, 2001.

57. Onaivi, E. S., Ali, S. F., Chirwa, S. S., Zwiller, J., Thiriet, N., Akinshola, B. E and Ishiguro H. Ibogaine signals addiction genes and methamphetamine alteration of long-term potentiation. Ann N Y Acad Sci 965: 28-46, 2002.

58. Onaivi, E. S., Leonard, C. M., Ishiguro, H., Zhang, P-W., Lin, Z., Akinshola, B. E. Uhl, G. Endocannabinoids and cannabinoid receptor genetics. Prog. Neurobiology 66:307-344, 2002.

59. Onaivi, E. S., Ishiguro, H., Lin, Z., Akinshola, B. E., Zhang, P-W and Uhl, G. R: Cannabinoid receptor genetics and behavior in: Onaivi, E. S (ed.), Biology of marijuana: from gene to behavior. London & New York: Taylor & Francis, 1-44, 2002.